When you need a kidney transplant, finding the best match can mean a more successful transplant. The better the match between the donor and recipient, the longer the transplanted kidney can last. How Does the NKR Find the Best Donor-Recipient Match for Kidney Transplants? Traditionally, kidney transplant matches were measured by an HLA match score from zero to six, with six being the best. HLA scores are generally based on A, B and DR antigens.
Except in cases of identical twins and some siblings, it is rare to get a six-antigen match between two people, especially if they are unrelated. Kidneys are very successfully transplanted between two people with no matching antigens. A person can make antibodies against another person’s HLA antigens.
At five years those numbers are 78.7% for 6/6 and 65.6% for 0/6. SRTR’s 2010 annual report shows a 10-year graft survival of non-extended criteria, deceased donor kidneys of 53.7% for 6/6 and 43.8% for 0/6. For living donor kidneys, the SRTR 2010 report shows a 10-year graft survival rate of 74.6% (6/6) vs 55.2% (0/0).
Moreover, what are the chances of being a kidney donor match? Siblings have a 25% chance of being an "exact match " for a living donor and a 50% chance of being a "half- match ." Donor compatibility is established through blood tests that look for matching blood types and antigens.
Living donor programs allow a relative or a compatible unrelated donor (such as a spouse or friend) to donate a kidney. Siblings have a 25% chance of being an "exact match" for a living donor and a 50% chance of being a "half-match." Donor compatibility is established through blood tests that look for matching blood types and antigens.
It is believed that the better the HLA match, the more successful the transplant will be over a longer period of time. Because of the way chromosomes/DNA are inherited or passed down in a family, a parent and child would have at least a 50 percent chance of matching, siblings could have a zero to 100 percent match, and unrelated donors would be less likely to match at all.
There are approximately 95,000 people on the waitlist list and the average wait time for a deceased kidney is 3 to 5 years. You can get on the waitlist for a kidney transplant when your GFR is 20 or below— before kidney failure. The sooner you can get on the list, the better. The United Network for Organ Sharing (UNOS) manages the national ...
The United States is divided into 11 regions and 58 local Organ Procurement Organizations (OPO)s, which are areas used to find matches for transplant. For example, if a kidney becomes available, UNOS will first try to find a match in the OPO where the kidney is being donated. If no match is found there, UNOS will search within the larger region.